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In this week's issue of The Lancet, we publish the latest global, regional, and national estimates and analyses from the Global Burden of Diseases, Injuries,... [Read More]
Globally, mortality rates have decreased across all age groups over the past five decades, with the largest improvements occurring among children younger than 5 years.... [Read More]
The past 37 years have featured declining rates of communicable, maternal, neonatal, and nutritional diseases across all quintiles of SDI, with faster than expected gains... [Read More]
The decrease in death rates since 1990 for most causes has not been matched by a similar decline in age-standardised YLD rates. For many large... [Read More]
At a global level, DALYs and HALE continue to show improvements. At the same time, we observe that many populations are facing growing functional health... [Read More]
Increasingly detailed understanding of the trends in risk exposure and the RRs for each risk-outcome pair provide insights into both the magnitude of health loss... [Read More]
People everywhere, but particularly those charged with improving the health of populations, want to know whether human beings are living longer and getting healthier. There... [Read More]
On June 1, 2017, the California Senate approved a bill (Senate Bill 562) to establish universal single-payer health care for all residents. This state legislation... [Read More]
Primary hyperparathyroidism is a common endocrine disorder of calcium metabolism characterised by hypercalcaemia and elevated or inappropriately normal concentrations of parathyroid hormone. Almost always, primary... [Read More]
The use of continuous glucose monitoring (CGM) has been increasing, especially in patients with type 1 diabetes, partly due to improved accuracy with lower mean... [Read More]
Use of CGM during pregnancy in patients with type 1 diabetes is associated with improved neonatal outcomes, which are likely to be attributed to reduced... [Read More]
The focus of cardiovascular disease prevention has shifted from normalisation of risk factors to absolute risk reduction. Reducing LDL cholesterol concentration by 1 mmol/L for... [Read More]
PCSK9 inhibition with evolocumab significantly reduced cardiovascular risk in patients with and without diabetes. Evolocumab did not increase the risk of new-onset diabetes, nor did... [Read More]
Regular use of electronic cigarettes (e-cigarettes) by 11–16 year olds is low (1–3%), and most experimental use does not lead to regular use or increase... [Read More]
A 68-year-old man with a 10-year history of progressive IgG λ multiple myeloma and chronic kidney disease presented with a 3-week history of a painful... [Read More]
A subgroup analysis of a phase 3 trial suggests that eribulin significantly improves survival outcomes compared with dacarbazine in patients with pretreated liposarcoma—a soft-tissue sarcoma... [Read More]
Of the estimated 696 million visits made by adults to US emergency departments between 2006 and 2012, 29·5 million (4·2%) were for cancer-related complications, according... [Read More]
Delayed nausea and vomiting induced by highly emetogenic chemotherapy could be significantly improved through a combination of thalidomide, palonosetron, and dexamethasone, new research suggests. [Read More]
Survival after childhood cancer has substantially improved over the past several decades, and more than 80% of children diagnosed with cancer in the USA now... [Read More]
The burden of CHCs in survivors of childhood cancer is substantial and highly variable. Our assessment of total cumulative burden in survivors of paediatric cancer,... [Read More]
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