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The assays that included a nucleic acid extraction followed by reverse transcription polymerase chain reaction were more sensitive than assays that lacked a full extraction.... [Read More]
Evidence is rapidly emerging on the effectiveness of tests for COVID-19 diagnosis and management, but important uncertainties about their effectiveness and most appropriate application remain.... [Read More]
Real-time reverse transcription-PCR (RT-PCR) is currently the most sensitive method to detect severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that causes coronavirus disease 2019 (COVID-19).... [Read More]
SARS-CoV-2 Vero cell infectivity was only observed for RT-PCR Ct < 24 and STT < 8 days. Infectivity of patients with Ct >24 and duration... [Read More]
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IRP senior investigator Julie Segre was elected to the National Academy of Medicine in 2019 in recognition of her pioneering research into microbial genomics. [Read More]
Larval tracheae of Drosophila harbour progenitors of the adult tracheal system (tracheoblasts). Thoracic tracheoblasts are arrested in the G2 phase of the cell cycle in... [Read More]
Exposure to patients with COVID-19 is significantly associated with higher burnout rates in physician trainees. [Read More]
Considering the RT-PCR Ct, which correlates with the estimated viral load, may help inform RTW planning and decision making beyond solely relying on dichotomized positive/negative... [Read More]
Hyperinflation contributes to dyspnea intensity in COPD. Little is known about the molecular mechanisms underlying hyperinflation and how inhaled corticosteroids (ICS) affect this important aspect... [Read More]
The down-classification of nodule malignancy risk with the Percepta test decreased additional invasive procedures without a delay in time to diagnosis among those with lung... [Read More]
Rationale: Early pathogenesis of lung adenocarcinoma (LUAD) remains largely unknown. We found that, relative to wild-type littermates, the innate immunomodulator lipocalin-2 (Lcn2) was increased in... [Read More]
Although nearly half of hospitalized smokers receiving support from a patient navigator received a prescription for a smoking cessation medication, the percentage did not differ... [Read More]
Background: Current tobacco treatment guidelines have established the efficacy of available interventions, but they do not provide detailed guidance for common implementation questions frequently faced... [Read More]
Prescription Medications to Help You Stop Smoking... [Read More]
Cerebral amyloid angiopathy (CAA) in Alzheimer's disease (AD)-deposition of beta amyloid (Aβ) within the walls of cerebral blood vessels-typically accompanies Aβ buildup in brain parenchyma... [Read More]
Myeloproliferative neoplasms (MPNs) are blood cancers that are characterized by the excessive production of mature myeloid cells and arise from the acquisition of somatic driver... [Read More]
Measurement of handgrip strength is a simple, risk-stratifying method for helping healthcare providers determine poorer cognitive functioning. Interventions aiming to prevent or delay cognitive dysfunction... [Read More]
An automatically generated Trainee Diversity Report will replace the manual report that signing officials are required to submit with RPPRs for most institutional training, career... [Read More]
Mice treated with apigenin had better memory and developmental milestone scores. [Read More]
NIH requires institutions to maintain an up-to-date, written, and enforced policy to identify and manage Investigator Financial Conflicts of Interest (FCOI) and to post the... [Read More]
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